《林浩然文集(上)(精)》是從林浩然院士截至
2013年發表的300多篇論文中選取120
篇編輯成上卷和下卷出版。本書以神經內分泌調控魚
類生殖和生長的
理論和技術為主線，內容共包括四篇。第一篇和第二
篇分別論述魚類
生殖和促性腺激素(GtH)分泌活動、魚類生長和生長
激素(GH)分泌活動
的神經內分泌調節作用機理；第三篇闡述調控魚類生
殖、生長和免疫
的相關激素及神經內分泌因子的功能基因，這三篇都
屬於基礎理論研
究成果。第四篇介紹促進養殖魚類生殖和生長、苗種
繁育和良種培育
的應用基礎研究和創新的新技術。這些論文展現了林
浩然院士和他的
研究團隊，以及國內外合作者在魚類生殖生理學和魚
類神經內分泌生
理學方面取得的創新性成果，同時亦顯示了我國學者
在這些學術領域
的國際學術地位和影響力。
本書可供魚類學、魚類生理學、魚類養殖生物學、
魚類內分泌學、魚
病學等相關領域的科學工作者和高等院校有關專業的
師生們學習參考。

《中國工程院院士文集》總序
序
前言
林浩然傳略
第一篇 魚類生殖和促性腺激素(GtH)分泌活動的神經內分泌調節作用機理
I 草魚一年多次產卵的生殖生理學基礎
草魚人工繁殖中一年多次產卵的生物學基礎
II 魚類促性腺激素(GtH)分泌活動和調節機理的基本特征
硬骨魚類的生殖內分泌學研究
硬骨魚類促性腺激素的分泌及其調節機制
高效能的促黃體素釋放激素類似物對金魚促性腺激素分泌的作用
促黃體素釋放激素及其高效類似物對銀**哈魚血漿促性腺激素和卵母細胞成熟的影響
魚類促性腺激素(GtH)的生理學和分子生物學一
DIRECT INFLUENCES OF TEMPERATURE ON GONADOTROPIN-II RELEASE FROM PERIFUSED
PITUITARY FRAGMENTS OF COMMON CARP(CYPRINUS CARPIOL.) IN VITRO
III 魚類生殖和促性腺激素(GtH)分泌活動受到下丘腦神經內分泌雙重調節的作用機理
利血平和丘腦下部促黃體素釋放激素類似物(LHRH-A)對大鱗副泥鰍促性腺激素細胞的分泌活動和
排卵的促進作用
硬骨魚類促性腺激素釋放激素類似物(t-GnRH-A)和Domperidone誘導鯉魚促性腺激素分泌和
排卵的作用
鮭魚促性腺激素釋放激素類似物和Domperidone誘導幾種養殖魚GtH分泌和排卵的研究
年齡對促黃體素釋放激素類似物(LHRH-A)刺激的和多巴胺能藥物抑制的鯉魚促性腺激素(GtH)
分泌的影響
脊椎動物促性腺激素釋放激素的分子結構變異型和功能多樣性
促性腺激素釋放激素(GnRH)結構與功能及其受體的進化發展
INDUCTION OF OVULATION IN THE LOACH(PARAMISGURNUS DABRYANUS) USING
PIMOZIDE AND [D-ALA6，PRO9-N-ETHYLAMIDE]-LHRH
EFFECTS OF [D-ALA6，PRO9-NET]-LHRH AND CATECHOLAMINERGIC DRUGS ON
GONADOTROPIN SECRETION AND OVULATION IN THE CHINESE LOACH
(PARAMISGURNUS DABRYANUS)
THE EFFECTS OF LHRH ANALOGUE AND DRUGS WHICH BLOCK THE EFFECTS OF DOPAMINE
ON GONADOTROPIN SECRETIoN AND OVULArl0N IN FISH CUIJURED IN CHINA
DOPAMINE INHIBITS GONADOTROPIN SECRETIoN IN THE CHINESE LOACH
(PARAMISGURNUS DABRYANUS)
EFFECTS OF GONADOTROPIN—RELEASING HORMONE AGONISTS AND DOPAMINE
ANTAGONISTS ON GONADOTROPIN SECRETl0N AND 0VULATl0N IN CHINESE
LOACH. PARAMISGURNUS DABRYANUS
TESTOSTERONE POTENTIATES THE SERUM GONADOTRoPIN RESPONSE TO GoNADOTROPIN.
RELEASING HORMONE IN THE COMMON CARP (CYPRINUS CARPIO) AND CHINESE
LOACH (PARAMISGURNUS DABRYANUS)
SEASONAL VARIATIONS IN GONADOTROPIN RESPONSIVENESS. SELF-PIuMING. AND
DESENSITIZATION TO GNRH PEPTIDES IN THE COMMON CARP PITUITARY IN VTRO
IV神經內分泌調節魚類生殖和促性腺激素(GtH)分泌活動的新模式
STRUCTURAL AND FUNCTl0NAL MUIJIPLICITY OF THE KISSPEPTIN／GPR54 SYSTEM IN
GOLDFISH (CARASSIUS AURATUS)
STRUCTURAL DIVERSITY 0F THE GNIH／GNIH RECEPTOR SYSTEM IN TELEOST：ITS
INVOLVEMENT IN EARLy DEVELOPMENT AND THE NEGATIVE CONTROL 0F LH
RELEASE
MOLECULAR IDENTIFICATION OF THE KISS2／KISS 1RA SYSTEM AND ITS POTENTIAL
FUNCTION DURING 17ALPHA—METHYLTESTOSTERONE. INDUCED SEX REVERSAL IN
THE ORANGE-SPOTTED GROUPER. EPINEPHELUS COIODES
SEXUAL DIMORPHISM OF STERoIDOGENESIS REGULATED BY GNIH IN THE GOLDFISH.
CARASSIUS AURATUS
EVIDENCES FOR THE REGULATl0N 0F GNRH AND GTH EXPRESSION BY GNIH IN THE
GOLDFISH. CARASSIUS AURATUS
第二篇 魚類生長和生長激素(GH)分泌活動的神經內分泌調節作用機理
I 魚類生長和生長激素(GH)分泌活動的特征
細胞外Ca2+和K+對鯉魚腦垂體離體生長激素分泌的影響
草魚血清生長激素水平的日變化
魚類生長和生長激素分泌活動的調節
鹽度變化對黑鯛生長激素及其受體的影響
THE GULATION OF GROWTH HORMONE SECRETION IN CARP
EPISODIC GROWTH HORMONE SECRETl0N IN THE GRASS CARP
CTENOPHARYNGODON IDELLUS(C.&V.)
II 魚類生長激素(GH)分泌活動的神經內分泌調節作用機理
促性腺激素釋放激素類似物促進魚類生長激素分泌和生長
鮭魚促性腺激素釋放激素(sGnRH)調節鯉魚腦垂體生長激素分泌的離體研究
兒茶酚胺類藥物對草魚生長激素分泌的影響
促黃體素釋放激素類似物和多巴胺對鯉魚幼魚和性成熟雌魚生長激素分泌的作用
神經內分泌因子調控魚類生殖和生長的相互作用
EFFECT OF CYSTEAMINE HYDROCHLORIDE ON GI己0WTH HORIⅥ0NE SECRETION FROM
HYPOTHALAMUS-PITUITARY TISSUE IN JUVENILE GRASS CARP(CTENOPHARYNGODON
IDELLUS)
SRIF及CSH對斜帶石斑魚腦垂體生長激素合成和分泌的調控
魚類生長激素合成與分泌的內分泌調控網絡：垂體生長激素分泌細胞中的信號整合
THE REGULATORY EFFECTS OF THYROTROPlN. RELEASING HORMONE ON GROWTH
HORMONE SECRETION FROM THE PITUITARY OF COMMON CARP IN VITRO
GROWTH HORMONE AND GONADOTROPIN SECRETION IN THE COMMON CARP(CYPRINUS
CARPIOL.)：IN VITRO INTERACTl0NS OF GONADOTROPIN-RELEASING HORMONE.
SOMATOSTATIN. AND THE DOPAMINE AGONIST APOMORPHlNE
EFFECTS OF GONADOTROPIN-RELEASING HORMONE(GNRH)ANALOGS AND SEX STEROIDS
ON GROWTH HORMONE(GH)SECRETIONAND GROWTH IN COMMON CARP fCYPRINUS
CARPIO)ANDGRASSCARP (CTENOPHARYNGODONIDELLUS)
EFFECTS OF GONADOTROPIN. RELEASING HORMONE ON GROWTH HORMONE SECRETl0N
AND GENE EXPRESSION IN COMMON CARP PITUlllARY
REGULATION OF GROWTH HORMONE RELEASE IN COMMON CARP PITUITARY CELLS BY
PITUITARYADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE: SIGNAL TRANSDUCTION
INVOLVES cAMP-AND CALCIUM-DEPENDENT MECHANISMS
LACK OF GROWTH HORMONE-RELEASING PEPTIDE-6 ACTION ON IN VIVO AND IN VITRO
GROWTH HORMONE SECRETION IN SEXUALLY IMMATURE GRASS CARP
(CTENOPHARYNGODONIDELLUS)
CYSTEAMINE-A SOMATOSTATIN-INHIBITING AGENT--INDUCED GROWTH HORMONE
SECRETION AND GROWTH ACCELERATl0N IN JUVENILE GRASS CARP
(CTENOPHARYNGODONIDELLUS)
STIMULATORY EFFECTS OF GONADOTROPIN. RELEASING HORMONE AND DOPAMINE ON
GROWTH HORMONE RELEASE AND GROWTH HORMONE mRNA EXPRESSION IN
EPINEPHELUS COIOIDES
RAT GHRELIN STIMULATES GH RELEASE AND GH mRNA EXPRESSION IN THE PITUITARY OF
ORANGE-SPOTTED GROUPER. EPlNEPHELUS COIOIDES
STIMULATORY EFFECTS OF NEUROPEPTIDE Y ON THE GROWTH OF ORANGE-SPOTTED
GROUPER (EINEPHELUS COIOIDES)
第三篇 調控魚類生殖、生長和免疫的相關激素與神經內分泌因子的功能基因
I 生殖調控方面
赤點石斑魚兩種芳香化酶cDNA的克隆及其表達的組織特異性
史氏鱘兩種促性腺激素β亞基cDNA克隆及序列進化分析
TWO DISTINCT CYTOCHROME P450 AROMATASES IN THE ORANGE. SPOTTED GROUPER
(EPINEPHELUSCOIOIDES)：cDNA CLONING AND DIFFERENTIAL mRNA EXPRESSION
DISCOVERY OF FOUR ESTROGEN RECEPTORS AND THEIR EXPRESSION PROFILES DURING
TESTIS RECRUDESCENCE IN MALE SPINIBARBUs DENTICULATUS
MOLECULAR CLONING,CHARACTERIZATION AND EXPRESSION PATTERN OF ANDROGEN
RECEPTOR IN SPINIBARBUS DENTICULATUS
MOLECULAR CHARACTERIZATIoN OF MARBLED EEL(ANGUILLA MARMORATA)
GONADOTROPIN SUBUNITS AND THEIR mRNA EXPRESSION PROFILES DURING
ARTIFICIALLY INDUCED GONADAL DEVELOPMENT
MOLECULAR CLONING AND FUNCTIONAL CHARACTERIZATl0N OF THE FIRST
NON-MAMMALIAN 26RFa／QRFP ORTHOLOGUE IN GOLDFISH，CARASSUS AURATUS
IDENTIFICATION OF A MEMBRANE ESTROGEN RECEPTOR IN ZEBRAFISH WITH HOMOLOGY
TO MAMMALIAN GPR30 AND ITS HIGH EXPRESSION IN EARLY GERM CELLS OF THE
TESTIS
DISTINCT EXPRESSION OF THREE ESTROGEN RECEPTORS IN RESPONSE TO BISPHENOL A
AND NONYLPHENOL IN MALE NILE TILAPIAS(OREOCHROMIS NILOTICUS)